What are endplate changes in spine?
Vertebral endplate (Modic) changes are bone marrow and endplate lesions visible in magnetic resonance imaging (MRI). They are shown to be associated with degenerative intervertebral disc disease [1–3]. Type II lesions (high T1 and T2 signals) are thought to manifest a more stable and chronic degeneration.
Is degenerative disc disease an autoimmune disease?
Recently, on the basis of in vitro experiments, a number of workers have suggested that degenerative disk desease may have an autoimmune basis.
Can degenerative disc disease affect your legs?
In some cases, degenerative disk disease can lead to numbness and tingling in your arms and legs. It can also cause your leg muscles to become weak. This means the damaged disks may be affecting the nerves near your spine.
Can C5-C6 cause shoulder pain?
Patients with C5 or C6 radiculopathy complain of shoulder area pain or shoulder girdle weakness. Typical idiopathic neuralgic amyotrophy (INA) is also characterized by severe shoulder pain, followed by paresis of shoulder girdle muscles.
What causes bone spurs on the endplates of the spine?
Bone spurs, also known as osteophytes, form along the edges of the vertebral endplates of the spine, according to the Laser Spine Institute. The body creates these spurs to support a weak spine. However, facet disease can remove the cartilage and cause the bones to grind against each other painfully.
What are bone marrow changes on a MRI?
These are vertebral endplate and subchondral bone marrow changes due to the degeneration of discs. These are observed on MRI as signal intensity changes in vertebral body near the end plates of the affected discs. With increasing age and repeated stress, wear and tear occurs in our back. This includes:
When does Modic degenerative endplate changes on MRI?
ii) Modic type 2 is when the marrow gets substituted by yellow fat. iii) Modic type 3 is the stage where all inflammation is finally replaced by bone scarring. Since your MRI is showing modic type 1 changes, you have active inflammation in your back adjacent to end plates, which is giving you the pain.
Can a bone marrow MRI show bone marrow edema?
Answer. An MRI picture is in black and white like an XRay but can provide cross sectional pictures from several different perspectives. “Bone marrow edema” can be seen in a number of different conditions. While the term “edema” implies fluid in the area, there are actually many different conditions that can cause this MRI finding.