Table of Contents
What Colour is ephedrine?
Ephedrine reacts with the expected blue colour, but the intensity of the colour is weak as compared to methamphetamine and to other secondary amines such as piperidine. The full development of the colour requires 5 to 10 minutes.
How do you identify ephedrine?
- Place small amount of material to be tested on a spot plate.
- Add 2 drops of reagent A.
- Add 2 drops of reagent B.
- Add 2 drops of reagent C.
- A violet color indicates presence of ephedrine or pseudoephedrine.
What is the generic name for ephedrine?
|Trade names||Akovaz, Corphedra, Emerphed, others|
|AHFS/Drugs.com||Ephedrine: Monograph HCl: Monograph Sulfate: Monograph|
|Pregnancy category||AU : A|
|Routes of administration||By mouth, intravenous (IV), intramuscular (IM), subcutaneous (SC)|
What is ephedrine used for?
Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis.
Is Ephedrine the same as epinephrine?
As a vasoconstrictor, epinephrine is 100 to 1,000 times more potent than ephedrine. 1 Mix-ups between these two drugs have resulted in serious patient harm.
What type of drug is ephedrine?
What is Ephedrine and how is it used? Ephedrine is a prescription medicine used to treat the symptoms of low blood pressure during anesthesia (Hypotension). Ephedrine may be used alone or with other medications. Ephedrine belongs to a class of drugs called Alpha/Beta Adrenergic Agonists.
What does ephedrine come from?
Ephedrine is a natural product of the ephedra plant (Ephedra sinica), and is a mixed-acting, noncatecholamine sympathomimetic with both direct and indirect stimulating effects on α- and β-adrenergic receptors.
Where is ephedrine absorbed in the body?
Ephedrine, synephrine, and caffeine are all well absorbed from the gastrointestinal tract. Following ingestion of an oral dose, clinical effects are seen within 60 min and persist from 2 to 6 h. Ephedrine is metabolized in the liver by oxidative deamination, demethylation, aromatic hydroxylation, and conjugation.
Does ephedrine help ADHD?
Amphetamines include amphetamine, dextroamphetamine, and lisdexamfetamine, which come in extended-release and immediate-release oral formulations. Methamphetamine, related to amphetamine and ephedrine and also an oral drug, is indicated for ADHD but also can increase blood pressure and reduce appetite.
What is the chemical structure of ephedrine tablets?
Ephedrine tablets. As a phenethylamine, ephedrine has a similar chemical structure to amphetamines and is a methamphetamine analogue having the methamphetamine structure with a hydroxyl group at the β position.
Is the D / L system the same as the ephedrine system?
In the outdated D / L system (+)-ephedrine is also referred to as L -ephedrine and (−)-ephedrine as D -ephedrine (in which case, in the Fisher projection, the phenyl ring is drawn at the bottom). Often, the D / L system (with small caps) and the d/l system (with lower-case) are confused.
How much ephedrine can a person have in their urine?
Blood or plasma ephedrine concentrations are typically in the 20-200 µg/l range in persons taking the drug therapeutically, 300-3000 µg/l in abusers or poisoned patients and 3–20 mg/l in cases of acute fatal overdosage. The current WADA limit for ephedrine in an athlete’s urine is 10 µg/ml.
What kind of optical isomerism does ephedrine have?
Ephedrine exhibits optical isomerism and has two chiral centres, giving rise to four stereoisomers. By convention, the pair of enantiomers with the stereochemistry (1R,2S) and (1S,2R) is designated ephedrine, while the pair of enantiomers with the stereochemistry (1R,2R) and (1S,2S) is called pseudoephedrine.