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What is a solvent for uric acid?

What is a solvent for uric acid?

Uric acid is virtually insoluble in water or common organic solvents, but it can be dissolved in basic solution such as aqueous solutions of Li2CO3 (1), KOH (2), NaOH(3), and ammonium hydroxide (4)(5).

What is the solubility of uric acid?

Water
Uric acid/Soluble in

Is uric acid highly soluble in water?

Uric acid is a purine derivative and an oxidative metabolic product of purine nucleotides in humans and other carnivorous animals. It is a weak acid with a pKa of 5.6 and is sparingly soluble in water….Uric acid fast facts.

CAS Reg. No. 69-93-2
Boiling point 310 ºC (dec.)
Water solubility 60 mg/L

How do I make uric acid solution?

Preparation of standards. Prepare a stock uric acid solution of 100 mg/L. Dilute it to give working concentrations of 5, 10, 20, 30, 40, and 50 mg/L. Weigh 100 mg uric acid, transfer to a 1 L volumetric flash, add about 900 ml distilled water, and then add about 100 µl of 0.6 N NaOH to help dissolve the uric acid.

What is the solute and solvent in urine?

Sodium and potassium, accompanied by univalent anions, and urea are the major urinary solutes; urea is normally predominant urinary solute during a strong antidiuresis [2;3]. The mechanisms for the independent control of water and sodium excretion are mostly contained within the renal medulla.

Is uric acid soluble in alcohol?

Water solubility This low solubility is significant for the etiology of gout. The solubility of the acid and its salts in ethanol is very low or negligible.

What is the melting point of uric acid?

572°F (300°C)
Uric acid/Melting point

What is the pH of uric acid?

Uric has a pKa of 5.75 and 10.3 and thus is a weak acid. The ionized forms of uric acid, urates, are present in synovial fluid and in plasma; approximately 98% exists as monosodium urate, with a pH of 7.4.

Is ammonia water soluble?

Ammonia gas is very soluble in water. The relatively high solubility is attributed to the hydrogen bonding that takes place between the ammonia and water molecules.

What kind of pH is ammonium urate found in?

Ammonium Urate Crystals. The presence of ammonium urate crystals is generally of little clinical significance. They are found in acidic urine (pH less than 6.5).

What causes the formation of ammonium urate crystals?

They are found in acidic urine (pH less than 6.5). The formation of ammonium urate crystals can be caused by a combination of factors including decreased urine volume or a condition that alkalinizes (increases the pH of) urine, such as a vegetarian diet, urinary tract infection or some medications.

When is ammonium chloride dissolved in water water is the solvent?

Solutions in which water is the solvent are called aqueous solutions. For e.g. when sugar is dissolved in water, the the solution obtained is called an aqueous solution and when ammonium chloride is dissolved in water, ammonium chloride is the solute and water is the solvent. Was this answer helpful?

Are there any patients with ammonium acid urolithiasis?

Unlike common calcium-containing stones, ammonium acid urate (AAU) urolithiasis is quite rare in patients with urinary stones (< 1%) [1]; however, AAU urolithiasis is still observed in developing countries, especially in Asia [2].