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Which of the following can be part of the extracellular matrix?

Which of the following can be part of the extracellular matrix?

Extracellular matrix (ECM) is an extensive molecule network composed of three major components: protein, glycosaminoglycan, and glycoconjugate. ECM components, as well as cell adhesion receptors, interact with each other forming a complex network into which cells reside in all tissues and organs.

Are glycoproteins attached to the extracellular matrix?

Cells are attached to the extracellular matrix, which is a network of molecules linked to each other. There are three adhesion mechanisms to maintain the structural integrity of tissues: cell-cell adhesions, cell-extracellular matrix adhesions, and linkages between molecules of the extracellular matrix. …

What are the two components of extracellular matrix?

Two main classes of extracellular macromolecules make up the matrix: (1) polysaccharide chains of the class called glycosaminoglycans (GAGs), which are usually found covalently linked to protein in the form of proteoglycans, and (2) fibrous proteins, including collagen, elastin, fibronectin, and laminin, which have …

Which of the following composes the extracellular matrix quizlet?

The extracellular matrix (ECM) surrounds the plasma membrane of animal cells and consists mainly of the glycoprotein collagen and sugar macromolecules called proteoglycans. The proteins of the ECM, including fibronectin, associate with protein receptors integrated into the cell surface, collectively known as integrins.

Where does extracellular matrix come from?

The extracellular matrix (ECM) is secreted by cells and surrounds them in tissues. It has long been understood to be the structural support for cells since its characteristics set the characteristics of the tissue (i.e. bone compared to cartilage compared to brain)1.

Is glycoprotein and proteoglycan same?

Proteoglycans are the proteins covalently attached to the glycosaminoglycans while glycoproteins are the proteins covalently attached to oligosaccharides. The main difference between proteoglycan and glycoprotein is the type of carbohydrates attached to the protein, the location, and the function.

What connects the cell to ECM?

ECM molecules connect to the cells through integrins, syndecans, and other receptors. Integrins are heterodimeric receptors composed of α and β subunits. In vertebrates, the family encompasses 18 α and 8 β subunits that can assemble into 24 different integrins.

How are cells attached to each other?

The cells are attached to each other by cell-cell adhesions, which bear most of the mechanical stresses. For this purpose, strong intracellular protein filaments (components of the cytoskeleton) cross the cytoplasm of each epithelial cell and attach to specialized junctions in the plasma membrane.

What structures make up the extracellular matrix?